Page 6 - L. Genetics and genomics

[L. Genetics and genomics-8]

Molecular study of Olfactory Receptor

Junho Lee¹

¹Biotechnology, Chonnam National University, Gwangju 61186, Korea

The olfactory nervous system recognizes and distinguishes many different chemicals in the general living
environment. Insects have evolved a group of odorant-gated ion channels composed of highly-developed olfactory
receptors capable of distinguishing and distinguishing between various chemicals with symbolic or evasive

specificities. Recently, aphid genomes related to olfaction, including olfactory receptors and proteins, have been

identified and olfactory receptors have been reported that are differentially differentiated from Drosophila. The
genome of the olfactory receptor has a very conservative sequence and a systematic signaling system. A
representative receptor, odorant-gated ion channels comprised of a highly conserved co-receptor (Orco) has a

homotetramer channel structure with four subunits arranged symmetrically around the central hole. It has a very
similar structure to the 7-transmembrane receptor present in the human body and has a very similar structural form

and gating mechanism to receptors of neurotransmitters.