Page 1 - C. Biotechnology and molecular imaging

Introduction of Laboratory Animal Resources Bank (LAREB)

Kyung-Ku Kang , Min-Soo Seo , Soo-Eun Sung , Joo-Hee Choi¹, SI-Joon Lee¹,
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Min-Kyung Sung¹, Kil-Soo Kim *
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1 Laboratory animal center, Daegu Gyeongbuk Medical Innovation Foundation, Daegu, Korea

Abstract

Laboratory animal Resources Bank (LAREB) is national infrastructure from National Institute of Food and

Drug Safety Evaluation (NIFDS, Korea) to utilize resources of laboratory animals that have been experimentally intervened.

After finishing the research, collecting resources from disused laboratory animals and sharing them with other researchers

will make the national infrastructure to reduce the research cost and shorten the research period. LAREB receives donated

resources through the core facility (DGMIF, Korea) which produces resources through primary processing from laboratory

animals received from universities, research institutes and pharmaceutical companies. Main resources are rare laboratory

animals, long-term drug treated animals, rare substance treated animals and animals that have undergone difficult surgery.

Donated resources are divided by organ and stored in formalin fixed, paraffin block, hematoxylin & eosin slide and frozen

tissue. LAREB has stored about 30,000 resources to date, the largest proportion of which is frozen tissue resources that can

generate secondary processing resources such as RNA and protein. Therefore, we think that it will can vitalize donation and

utilization of resources through various and continuous publicity of LAREB. By operating the LAREB, we expect to strengthen

research competitiveness, create diverse results from one study, and create new industries for high value-added laboratory

animals and resources.

Laboratory Animal Resources Bank (LAREB) Resource type stored in LAREB

LAREB DGMIF

(Core facility)

LAREB

Comparison of workflow

Resource Resource

Donation Core facility Utilization

University Laboratory Company

Resource Processing & Storing System

Barcode, Database

Processing

Fixed tissue Paraffin block H&E Slide

Resource

Donation

Necropsy Tissue

Frozen Tissue