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KSBMB

DDR is regulated by post-translational modification. Ubiquitination, one of post-translation modification in DDR, was regulated by E3 ubiquitin ligase…

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[F. Others] F-1 Nephronophthisis 3 regulates cancer cell growth by primary cilium formation through reactive oxygen species-induced HIF-1alpha and Erk Jae-Wook Lee1, Eun-Yi Moon1* 1Department of Integrative Bioscience and Biotechnology, Sejong University, Seoul 05006, Korea Primary cilium is antenna-like organelle projecting from the surface of cell membrane. We reported previously that primary cilium formation could be regulated by nephronophthisis 3 (NPHP3) expression followed by its interaction with by thymosin β4 using HeLa cervical cancer cells.

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Genetic assessment of GABBR2 in human brain development Jeongha Lee , Sung-gyun Park2, Byung Joon Hwang2, Murim Choi 1 1 Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea 2Department of Molecular Bioscience, Kangwon National University College of Biomedical Science, Seoul, Republic of Korea ABSTRACT RESURTS We had previously elucidated the mechanism of pathogenic 1. Table of GABBR2 pathogenic variant carriers. 4.

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[F. Others] F-9 Deep Y: AI-based biosimilarity assessment platform for antibody drugs using intact glycoproteins analysis Dae Sik Cho1,2, Hee Youn Hwang3, Myung Jin Oh1,2, Hyun Joo An1,2* 1Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 34134, Korea, 2Asia-Pacific Glycomics Reference Site, Chungnam National University, Daejeon 34134, Korea, 3Division of Bioconvergence Analysis, Korea Basic Science Institute, Ochang 28119, Korea A biosimilar is a biological drug that is nearly identical to the original product.

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C-to-G Base Editing Increases Oleic Acid Production without any growth defects 1,2 Mid-Eum Park , Yuli Choe , Hyun Uk Kim * 1 Department of Molecular Biology, Plant Engineering Research Institute, Sejong University, Seoul 05006, Korea, 2 Department of Bioindustry and Bioresource Engineering, Plant Engineering Research Institute, Sejong University, Seoul 05006, Korea Abstract A B The demand for vegetable oil is steadily increasing worldwide for dietary purposes and cooking.

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[F. Others] F-18 Ubiquitin binding protein TRIM44 is a candidate as a novel regulator of DNA damage response Yonghyeon Kim1, Jae-Hoon Ji1, Sunwoo Min1, Yungyeong Heo1, Hyeseong Cho1* 1Department of Biochemistry, Ajou university, Suwon 16499, Korea DNA damage response (DDR) is essential for maintaining genome stability. DDR is regulated by post-translational modification. Ubiquitination, one of post-translation modification in DDR, was regulated by E3 ubiquitin ligase and de-ubiquitin enzyme(DUB).

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SPINT2 is a key effector of DNMT1 to regulate the entry into senescence. Min Seok Sim 1,2,3 , Seongki Min 1,2,3 and Gyesoon Yoon 1,2,3 1 Department of Biochemistry & Molecular Biology, Ajou University School of Medicine, Suwon 16499, Korea 2 Inflamm-aging Translational Research Center, Ajou University Medical Center, Suwon 16499, Korea 3 Department of Biomedical Science, The Graduate School, Ajou University, Suwon 16499, Korea ABSTRACT As senescence develops, cells sequentially acquire diverse senescent phenotypes along with simultaneous stage-specific gene reprogramming.

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