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출처: 이북나라 전자책 『KSBMB』 2쪽 · 3쪽 · 5쪽 · 6쪽 · 8쪽 · 9쪽. 원문에 없는 주제·저자·발행일은 넣지 않았습니다.

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[C. Omics & Fusion Biology] C-1 PPARγ Targets-Derived Diagnostic and Prognostic Index for Papillary Thyroid Cancer Jaehyung Kim1 , Soo Young Kim2 , Shi-Xun Ma3, Su-Jin Shin5, Yong Sang Lee4, Hojin Chang4, Hang-Seok # # Chang4, Cheong Soo Park6, Seok-Mo Kim4*, Su Bin Lim1* 1Department of Biochemistry & Molecular Biology, Ajou University School of Medicine, Suwon 16499, Korea, 2Department of Surgery, Ajou University School of Medicine, Suwon 16499, Korea, 3Department of Neurology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore MD 21205, USA, 4Department…

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2022 KSBMB Winter Workshop PPARγ Targets-Derived Diagnostic and Prognostic Index for Papillary Thyroid Cancer 4, Jaehyung Kim 1,†,# , Soo Young Kim , Shi-Xun Ma , Seok-Mo Kim * , Su-Jin Shin , Yong Sang Lee , Hojin Chang , Hang-Seok Chang , Cheong Soo Park and Su Bin Lim * 2,† 1, 1 Department of Biochemistry & Molecular Biology, Ajou University School of Medicine, Suwon 16499, Korea, 2 Department of Surgery, Ajou University School of Medicine, Suwon 16499, Department of Neurology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA, Thyroid…

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Gene Expression Data ACTR2 Down • GSE68719 from NCBI GEO database • 29 PD patients and 44 control samples 2. Drug Data Top ranked drug analysis • 13,581 drugs with target and indication information from the Drugbank 2 3. Network Construction Top 5 Drug Targets with Drugs Top Drug Targets Category • Construct directed Network by union of the KEGG and the Pathway Commons • Pruning the node of network without gene expression data Targets Score Drug name 1. Used in clinical trial • The network contains 15,364 nodes and 397,189 edges Chlorotrianisene • Conducted trials for PD 4.

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[C. Omics & Fusion Biology] C-3 Comparative phosphoproteomics of Neuro-2a cells under insulin resistance reveals new molecular signatures of Alzheimer’s disease Yeon Suk Jo1,2, Han Seul Jo1, Sung won Bae1, Yang Woo Kwon1, Dayea Kim3*, Yong Seok Oh2*, Jong Hyuk Yoon1* 1Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu 41062, Korea, 2Department of Brain-Cognitive Science, Daegu-Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea, 3New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea Insulin is a…

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[C. Omics & Fusion Biology] C-4 Mouse Brain N-Glycome DB: Investigation of brain region- specific N-glycome diversity using nanoLC-MS/MS Dongtan Yin1,2, Hee Young Jo1,2, Hyun Joo An1,2* 1Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 34134, Korea, 2Asia-pacific Glycomics Reference Site, Chungnam National University, Daejeon 34134, Korea In the mammalian brain, over 70% of proteome is known to be glycosylated, and a large fraction of the glycosylation is N-glycome.

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Mouse Brain N-Glycome DB: Investigation of brain region-specific N-glycome diversity using nanoLC-MS/MS Dongtan Yin , Hee Young Jo , Hyun Joo An * 1,2 1,2 1,2 1 Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon, 34134, Korea 2 Asia-pacific Glycomics Reference Site, Daejeon, 34134, Korea Overview Result Glycosylation is one of the most structurally complicated forms of post- Elucidation of glycan structures by MS/MS translational modification of proteins.

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