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출처: 이북나라 전자책 『H. Cell signaling』 1쪽 · 7쪽 · 13쪽 · 20쪽 · 26쪽 · 32쪽. 원문에 없는 주제·저자·발행일은 넣지 않았습니다.

H. Cell signaling

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Arginase II down regulation recovers Ca /CaMKII-Akt-eNOS signaling and 2+ vascular homeostasis in p32 over expressed. Bon-hyeock Koo, Sungwoo Ryoo Department of Biology, College of Natural Sciences, Kangwon National University, Chuncheon 200-701, Republic of Korea BACKGROUND Methods ● Maintaining vascular homeostasis is important physiologically for vascular systems. ● Electron microscopy (EM) ● Intracellular Ca 2+ signaling between mitochondria and cytosol which is regulated by mitochondrial p32 ● Mitochondrial fractionation and their mechanism is important for vascular homeostasis.

출처: 이 전자책 1쪽

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p32 conditional knock out of endothelium was increased vascular function via activation of CaMKll/AMPK/p38 MAPK/Akt/eNOS axis Byeongjun Yoon and Sungwoo Ryoo Department of Biology, College of Natural Sciences, Kangwon National University, Chuncheon 200-701, Republic of Korea ABSTRACTS INTRODUCTIONS ● The decrease in expression of p32 induced the activity of the CaMKll/AMPK ● Ca 2+ is a major secondary messenger and can induce various cellular 2+ /p38 MAPK/Akt/eNOS signaling pathway responses, which can activate Ca /calmodulin-dependent protein kinasell (CaMKll) and endothelial nitric oxide…

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본문 13쪽

Development of a IGF-1R/Src/Axl inhibitor as a novel anticancer agent with reduced toxicity Ho Jin Lee, Honglan Pei, Seung Yeob Hyun,Hye-Young Min, Ho-Young Lee* S eoul National University, Seoul 08826, Republic of Korea abstract The type I insulin-like growth factor receptor (IGF-1R) signaling pathway plays key roles in the development and progression of numerous types of human cancers, and Src and AXL have been found to confer resistance to anti-IGF-1R therapies. Hence, co-targeting Src and AXL may be an effective strategy to overcome resistance to anti-IGF-1R therapies.

출처: 이 전자책 13쪽

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[H. Cell signaling-17] Nitration of protein phosphatase 2A increases via Epac1/PLCε/CaMKII/HDAC5/iNOS cascade in human endometrial stromal cell decidualization So Young Lee1, Shin-Young Park2, Yung Young Lee1, Jun Hyeon Jeong1, Jung-Sub Choi3, Kyeong Soo Kim4, Do Sik Min5, Joong-Soo Han1 ̇2 1Biomedical Sciences, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 03172, Republic of Korea, 2Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul 03172, Republic of Korea, 3Obstetrics and Gynecology, College of Medicine, Hanyang…

출처: 이 전자책 20쪽

본문 26쪽

[H. Cell signaling-20] Gallotannin regulates differentiation by changing Actin cytoskeleton and cell morphology in Human osteoblast-like Saos-2 cells Byung Su Ko1, Song Ja Kim1 ̇* 1Department of Biological science, Kongju National University, Gongju 32588, Republic of Korea Gallotannin (GT) is a class of polyphenols with antioxidant, anticancer, and antiviral activities. GT in primary-cultured chondrocytes enhances expression of type ii collagen, an indicator of differentiation. However, the effect of differentiation is not clear in Human osteoblast-like Saos-2 cells.

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[H. Cell signaling-25] Role of mTORC2 in NK cell-mediated cytotoxicity against tumor cells Jaeho Cho1, Mirae Kim1, Gyu Tae Park1, Sung Su Yea1 1Dept. of Biochemistry, Inje University College of Medicine, Busan 47392, Korea Recently, isoform-specific inhibitors of phosphoinositide 3-kinase (PI3K) and mechanistic target of rapamycin (mTOR) are being evaluated for their therapeutic potential in cancer. However, little is known about their roles in natural killer (NK) cell.

출처: 이 전자책 32쪽